Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622487 | 0.93 | DNM1 (0.39) | DNM1MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL28027706 | 0.91 | DNM1 (0.44) | DNM1MEN1KMT2ASMN1; SMN2TP53 | |
| Sulfuric Acid SCHEMBL2908891 | 0.91 | DNM1 (0.49) | DNM1MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL331108 | 0.89 | DNM1 (0.47) | DNM1MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL330958 | 0.89 | DNM1 (0.47) | DNM1MEN1KMT2ASMN1; SMN2TP53 | |
| Sulfuric Acid SCHEMBL2245785 | 0.89 | DNM1 (0.47) | DNM1MEN1KMT2ASMN1; SMN2TP53 | |
| Sulfuric Acid SCHEMBL2245787 | 0.88 | DNM1 (0.46) | DNM1MEN1KMT2ASMN1; SMN2TP53 | |
| Sulfuric Acid SCHEMBL17272951 | 0.86 | DNM1 (0.45) | DNM1MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL331061 | 0.85 | DNM1 (0.44) | DNM1MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL330995 | 0.85 | DNM1 (0.44) | DNM1MEN1KMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985664-B1 | Method of producing pyrrolidine derivatives | TORAY FINECHEMICALS CO LTD (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6479668-B1 | Method of producing pyrrolidine derivatives | TORAY INDUSTRIES, INC. (JP) | 2002-11-12 | — | — | US | disclosed |
| US-6130338-A | OXIDATING THE CORRESPONDING 3-PYRROLINE COMPOUND TO GIVE AN EPOXYPYRROLIDINE COMPOUND | TORAY INDUSTRIES, INC. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0985664-A2 | Method of producing pyrrolidine derivatives | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |