Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617376 | 1.00 | F10 (0.40) | F10MAOAFADS1F2ITGB3 | |
| SCHEMBL6646055 | 1.00 | F10 (0.40) | F10MAOAFADS1F2ITGB3 | |
| SCHEMBL6617609 | 0.91 | MAOA (0.47) | F10MAOAFADS1F2 | |
| SCHEMBL6040255 | 0.84 | F10 (0.45) | F10MAOAFADS1F2GRM2 | |
| SCHEMBL5762074 | 0.84 | F10 (0.45) | F10MAOAFADS1F2GRM2 | |
| SCHEMBL6616513 | 0.83 | MAOA (0.57) | F10MAOAFADS1 | |
| SCHEMBL6617209 | 0.83 | MAOA (0.57) | F10MAOAFADS1 | |
| SCHEMBL5221394 | 0.78 | F10 (0.52) | F10MAOAF2 | |
| SCHEMBL5766169 | 0.75 | F10 (0.41) | F10MAOAFADS1F2GRM2 | |
| SCHEMBL5763275 | 0.75 | F10 (0.41) | F10MAOAFADS1F2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451164-A2 | AMIDE DERIVATIVES HAVING IMPROVED SOLUBILITY | PHARMACIA & UPJOHN COMPANY (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003006440-A2 | AMIDE-CONTAINING COMPOUND HAVING IMPROVED SOLUBILITY AND METHOD OF IMPROVING THE SOLUBILITY OF AN AMIDE-CONTAINING COMPOUND | PHARMACIA & UPJOHN COMPANY (US) | 2003-01-23 | — | — | WO | disclosed |