Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.65 |
| ▸ | ACACA | Q13085 | 6/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977641 | 0.86 | ACACB (0.86) | ACACBACACACHRM3KDM2BGAA | |
| SCHEMBL977639 | 0.86 | ACACB (0.86) | ACACBACACACHRM3KDM2BGAA | |
| SCHEMBL6620653 | 0.80 | ACACB (0.68) | ACACBACACACHRM3KDM2BGAA | |
| SCHEMBL976549 | 0.79 | ACACB (1.00) | ACACBACACACHRM3 | |
| SCHEMBL3459079 | 0.79 | ACACB (1.00) | ACACBACACACHRM3 | |
| Hydrochloric Acid SCHEMBL6181697 | 0.79 | ACACB (0.98) | ACACBACACACHRM3 | |
| SCHEMBL6182670 | 0.76 | ACACB (0.93) | ACACBACACACHRM3 | |
| SCHEMBL6186087 | 0.71 | ACACB (0.73) | ACACBACACACHRM3KDM2BGAA | |
| SCHEMBL6183505 | 0.71 | ACACB (0.84) | ACACBACACAKDM2BGAA | |
| SCHEMBL2622325 | 0.70 | ACACB (0.83) | ACACBACACAKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-A1 | ACC INHIBITORS | Pfizer Products Inc. (US) | 2004-11-24 | — | — | EP | claimed |
| WO-2003072197-A1 | ACC INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | claimed |