SCHEMBL976549

SCHEMBL976549

O=C(c1c2ccccc2cc2ccccc12)N1CCC(N2CCC[C@@H](C(=O)N3CCOCC3)C2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACACB O00763 14/20 1.00
ACACA Q13085 14/20 1.00
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
L3MBTL3 Q96JM7 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CHRM3 P20309 1/20 0.46
ADRA1A P35348 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3459079 1.00 ACACB (1.00) ACACBACACAMEN1KMT2AL3MBTL3
Hydrochloric Acid SCHEMBL6181697 0.99 ACACB (0.98) ACACBACACAMEN1KMT2AL3MBTL3
SCHEMBL6182670 0.96 ACACB (0.93) ACACBACACAMEN1KMT2AL3MBTL3
SCHEMBL977641 0.93 ACACB (0.86) ACACBACACACHRM3
SCHEMBL977639 0.93 ACACB (0.86) ACACBACACACHRM3
SCHEMBL6183505 0.92 ACACB (0.84) ACACBACACAL3MBTL3L3MBTL1
SCHEMBL976349 0.91 ACACB (0.83) ACACBACACAL3MBTL3L3MBTL1
SCHEMBL2622325 0.91 ACACB (0.83) ACACBACACAL3MBTL3L3MBTL1
SCHEMBL6181556 0.89 ACACB (0.80) ACACBACACA
SCHEMBL6491415 0.88 ACACB (0.78) ACACBACACAL3MBTL3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024192080-A1 METHODS OF TREATING, PREVENTING, AND/OR AMELIORATING CANCER WITH ACETYL COENZYME A (COA) CARBOXYLASE INHIBITOR(S) YALE UNIVERSITY (US) 2024-09-19 WO claimed
EP-4408980-A2 LINEAGE SPECIFICATION DURING STEM CELL TRANSITION Amniotics AB (SE) 2024-08-07 EP claimed
WO-2023052650-A2 LINEAGE SPECIFICATION DURING STEM CELL TRANSITION AMNIOTICS AB (SE) 2023-04-06 WO claimed
EP-3964206-A1 COMPOUNDS FOR THE TREATMENT OF COVID-19 Dompe' Farmaceutici S.P.A. (IT) 2022-03-09 EP claimed
US-20210137934-A1 METHODS OF IDENTIFYING MYC-DRIVEN AND LIPOGENESIS-DEPENDENT NEOPLASMS AND METHODS OF TREATING THE SAME THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2021-05-13 US claimed
EP-2150265-A1 INHIBITORS OF ACETYL-COA CARBOXYLASE FOR TREATMENT OF NEURONAL HYPOMETABOLISM Neuera Pharmaceuticals, Inc. (US) 2010-02-10 EP claimed
WO-2008140828-A1 INHIBITORS OF ACETYL-COA CARBOXYLASE FOR TREATMENT OF NEURONAL HYPOMETABOLISM ACCERA, INC. (US) 2008-11-20 WO claimed
EP-1478437-B1 ACC INHIBITORS PFIZER PROD INC (US) 2005-08-31 EP claimed
US-20030187254-A1 Acetyl-CoA carboxylase inhibitors PFIZER INC. 2003-10-02 US claimed
EP-4611792-A1 THERAPEUTIC REGIMENS AND METHODS FOR TREATMENT OF CARDIOVASCULAR RISK FACTORS USING A GLP-1R AND GCGR AGONIST Spitfire Pharma LLC (US) 2025-09-10 EP disclosed
CN-119732910-A SiRNA nano liposome and application thereof in preparation of drugs for treating non-alcoholic fatty liver disease 浙江工业大学 2025-04-01 CN disclosed
WO-2024192080-A1 METHODS OF TREATING, PREVENTING, AND/OR AMELIORATING CANCER WITH ACETYL COENZYME A (COA) CARBOXYLASE INHIBITOR(S) YALE UNIVERSITY (US) 2024-09-19 WO disclosed
EP-4408980-A2 LINEAGE SPECIFICATION DURING STEM CELL TRANSITION Amniotics AB (SE) 2024-08-07 EP disclosed
US-11737995-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-29 US disclosed
WO-2008140828-A1 INHIBITORS OF ACETYL-COA CARBOXYLASE FOR TREATMENT OF NEURONAL HYPOMETABOLISM ACCERA, INC. (US) 2008-11-20 WO disclosed
WO-2008137435-A1 [6,6] AND [6,7]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-11-13 WO disclosed
WO-2008137436-A1 [6,5]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-11-13 WO disclosed
US-6979741-B2 Acetyl-CoA carboxylase inhibitors PFIZER INC. (US) 2005-12-27 US disclosed
EP-1478437-B1 ACC INHIBITORS PFIZER PROD INC (US) 2005-08-31 EP disclosed
US-20030187254-A1 Acetyl-CoA carboxylase inhibitors PFIZER INC. 2003-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11737995-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease AHR, PKD1, CFTR ACACB 1431/4885ACACA 1244/4885MEN1 3434/4885
US-20030187254-A1 Acetyl-CoA carboxylase inhibitors ACACA, ACACB, ACAT1 ACACB 2/4885ACACA 1/4885MEN1 3712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.