Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 7/20 | 0.39 |
| ▸ | RARG | P13631 | 6/20 | 0.39 |
| ▸ | RARA | P10276 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766851 | 0.88 | S1PR1 (0.37) | HDAC11HDAC2RARBRARGRARA | |
| SCHEMBL6622319 | 0.86 | RARB (0.39) | HDAC11HDAC2RARBRARGRARA | |
| SCHEMBL6618558 | 0.86 | HDAC11 (0.42) | HDAC11HDAC2RARBRARGRARA | |
| SCHEMBL404472 | 0.82 | HDAC11 (0.49) | HDAC11HDAC2RARBRARGRARA | |
| SCHEMBL6704746 | 0.81 | FAAH (0.46) | HDAC11HDAC2RARBRARGRARA | |
| SCHEMBL6619613 | 0.80 | RARB (0.39) | HDAC11HDAC2RARBRARGRARA | |
| SCHEMBL7683467 | 0.79 | HDAC11 (0.36) | HDAC11HDAC2RARBRARGRARA | |
| SCHEMBL5827849 | 0.79 | HDAC11 (0.38) | HDAC11HDAC2RARBRARGRARA | |
| SCHEMBL6706257 | 0.79 | RARB (0.39) | HDAC11HDAC2RARBRARGRARA | |
| SCHEMBL399513 | 0.78 | HDAC11 (0.47) | HDAC11HDAC2RARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463718-A1 | 2-SUBSTITUTED THIAZOLIDINONE AND OXAZOLIDINONE DERIVATIVES FOR THE INHIBITION OF PHOSPHATASES AND THE TREATMENT OF CANCER | Incyte San Diego Incorporated (US) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003050098-A1 | 2-SUBSTITUTED THIAZOLIDINONE AND OXAZOLIDINONE DERIVATIVES FOR THE INHIBITION OF PHOSPHATASES AND THE TREATMENT OF CANCER | INCYTE SAN DIEGO INCORPORATED (US) | 2003-06-19 | — | — | WO | disclosed |