⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2081452 | 0.78 | — | — | |
| SCHEMBL22774824 | 0.74 | — | — | |
| SCHEMBL4699959 | 0.74 | — | — | |
| SCHEMBL1696277 | 0.74 | — | — | |
| SCHEMBL4950183 | 0.74 | — | — | |
| SCHEMBL7822870 | 0.74 | — | — | |
| SCHEMBL31556324 | 0.74 | CYP3A4 (0.44) | — | |
| SCHEMBL5104539 | 0.74 | ALOX5 (0.42) | — | |
| Hydrochloric Acid SCHEMBL9984331 | 0.72 | IDO1 (0.42) | — | |
| SCHEMBL29958333 | 0.72 | ALOX5 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474140-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | Pharmagene Laboratories Ltd (GB) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068226-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |