Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4828419 | 0.93 | NR4A1 (0.50) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL4099062 | 0.86 | NR4A1 (0.57) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL4831542 | 0.78 | NR4A1 (0.47) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL27883139 | 0.74 | KMT2A (0.50) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL4109121 | 0.73 | NR4A1 (0.53) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL32665708 | 0.72 | NR4A1 (0.61) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL5716814 | 0.72 | NR4A1 (0.61) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL28924687 | 0.72 | CES2 (0.47) | ADRB2ADRB1ADRB3ALDH1A1KMT2A | |
| SCHEMBL2599098 | 0.71 | NR4A1 (0.59) | NR4A1NR4A2NR4A3PTPN1PLK1 | |
| SCHEMBL2599103 | 0.71 | NR4A1 (0.59) | NR4A1NR4A2NR4A3PTPN1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474140-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | Pharmagene Laboratories Ltd (GB) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068226-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |