Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537127 | 0.73 | KDM4E (0.39) | KDM4EGPR3MAPK1 | |
| SCHEMBL2522030 | 0.73 | KDM4E (0.39) | KDM4EGPR3MAPK1 | |
| SCHEMBL1043402 | 0.70 | CYP2B6 (0.43) | KDM4ECYP2B6CYP19A1 | |
| SCHEMBL29372595 | 0.70 | CYP2B6 (0.43) | KDM4ECYP2B6CYP19A1 | |
| SCHEMBL29365059 | 0.70 | CYP2B6 (0.43) | KDM4ECYP2B6CYP19A1 | |
| SCHEMBL976367 | 0.68 | KDM4E (0.40) | KDM4EGPR3MAPK1 | |
| SCHEMBL5093546 | 0.67 | KDM4E (0.39) | KDM4EGPR3 | |
| SCHEMBL30343302 | 0.67 | KDM4E (0.39) | KDM4EGPR3 | |
| SCHEMBL378548 | 0.67 | KDM4E (0.39) | KDM4EGPR3 | |
| SCHEMBL5902340 | 0.67 | KDM4E (0.39) | KDM4EGPR3CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230232-B1 | SUBSTITUTED 4H-CHROMENE AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA INC (US) | 2004-02-25 | — | — | EP | claimed |
| EP-1230232-A2 | SUBSTITUTED 4H-CHROMENE AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | Cytovia, Inc. (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001034591-A2 | SUBSTITUTED 4H-CHROMENE AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2001-05-17 | — | — | WO | claimed |