Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28262113 | 1.00 | KDM4E (0.39) | KDM4EGPR3ALDH1A1PARP1PRKCI | |
| Hydrochloric Acid SCHEMBL6555973 | 0.98 | KDM4E (0.38) | KDM4EGPR3ALDH1A1PARP1PRKCI | |
| SCHEMBL27619154 | 0.98 | KDM4E (0.38) | KDM4EGPR3ALDH1A1PARP1PRKCI | |
| SCHEMBL27619538 | 0.98 | KDM4E (0.38) | KDM4EGPR3ALDH1A1PARP1PRKCI | |
| SCHEMBL27971102 | 0.89 | ALDH1A1 (0.33) | KDM4EGPR3ALDH1A1PARP1PRKCI | |
| SCHEMBL15994595 | 0.84 | TDP1 (0.39) | KDM4EGPR3ALDH1A1HSD17B10TDP1 | |
| SCHEMBL31277019 | 0.84 | ALDH1A1 (0.38) | KDM4EGPR3ALDH1A1PARP1PRKCI | |
| SCHEMBL29176096 | 0.82 | KDM4E (0.38) | KDM4EGPR3AKT1 | |
| SCHEMBL28080700 | 0.82 | KDM4E (0.38) | KDM4EGPR3AKT1 | |
| SCHEMBL28571883 | 0.78 | ABL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 710 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119643099-A | Pipeline thermal cycle visual test system and method | 中国核电工程有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119491239-A | Electrochemical catalytic synthesis method of phenanthridone | 南通诺泰生物医药技术有限公司 | 2025-02-21 | — | — | CN | claimed |
| CN-119059968-A | Synthesis method of phenanthridinone compound based on visible light catalysis | 安徽工程大学 | 2024-12-03 | — | — | CN | claimed |
| CN-118880358-A | Method for electrochemically synthesizing phenanthridinone and spiro oxindole compound | 桂林医学院 | 2024-11-01 | — | — | CN | claimed |
| US-20240245643-A1 | DNA Damage Repair Inhibitors for Treatment of Cancer | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2024-07-25 | — | — | US | claimed |
| CN-118159526-A | Process for preparing chloroalkyl substituted cyclic amines | 好利安药理股份公司 | 2024-06-07 | — | — | CN | claimed |
| CN-118040096-A | Application of aqueous electrolyte capable of regulating relaxation time in zinc metal negative electrode and zinc battery | 广东工业大学 | 2024-05-14 | — | — | CN | claimed |
| CN-117924171-A | Phenanthrone derivative and synthesis method thereof | 华南理工大学 | 2024-04-26 | — | — | CN | claimed |
| US-20230383363-A1 | METHOD FOR DETERMINING SENSITIVITY TO PARP INHIBITOR OR DNA DAMAGING AGENT USING NON-FUNCTIONAL TRANSCRIPTOME | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2023-11-30 | — | — | US | claimed |
| CN-116879432-A | Method for detecting content of fenidone in aquatic product | 厦门鉴科检测技术有限公司 | 2023-10-13 | — | — | CN | claimed |
| US-5877278-A | SOLID PHASE SYNTHESIS USING TWO SUBMONOMERS-AN ACYLATING AGENT, E.G. A HALOACETIC ACID, AND A PRIMARY AMINE; CYCLIZATION TO PRODUCE MIMETICS OF DRUGS; ELIMINATION OF THE NECESSITY OF PROTECTION GROUPS | CHIRON CORPORATION (US) | 1999-03-02 | — | — | US | claimed |
| US-5874444-A | CONTROLLING CELL AGING | GERON CORPORATION (US) | 1999-02-23 | — | — | US | claimed |
| EP-0789577-A4 | SYNTHESIS OF N-SUBSTITUTED OLIGOMERS | CHIRON CORP (US) | 1998-07-22 | — | — | EP | claimed |
| EP-0789577-A1 | SYNTHESIS OF N-SUBSTITUTED OLIGOMERS | CHIRON CORPORATION (US) | 1997-08-20 | — | — | EP | claimed |
| WO-1996040202-A1 | SYNTHESIS OF N-SUBSTITUTED OLIGOMERS | CHIRON CORPORATION (US) | 1996-12-19 | — | — | WO | claimed |
| US-5214139-A | 2-phenanthridonyl-carbapenems | MERCK & CO., INC. (US) | 1993-05-25 | — | — | US | claimed |
| US-5208328-A | Intermediates for antibiotics and bactericides | MERCK & CO., INC. (US) | 1993-05-04 | — | — | US | claimed |
| EP-0509780-A1 | 2-phenanthridonyl carbapenems | MERCK & CO. INC. (US) | 1992-10-21 | — | — | EP | claimed |
| EP-0509756-A1 | 2-Phenanthridonyl carbapenems having cationizeable substituents | MERCK & CO. INC. (US) | 1992-10-21 | — | — | EP | claimed |
| US-5153185-A | Antibiotics for methicillin resistant Staphylococcus strains | MERCK & CO., INC. (US) | 1992-10-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245643-A1 | DNA Damage Repair Inhibitors for Treatment of Cancer | PARP2, MRE11, PARP1 | KDM4E 2660/4885GPR3 4004/4885ALDH1A1 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.