Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623302 | 0.87 | KDM4E (0.42) | KDM4ESMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL6625277 | 0.86 | KDM4E (0.45) | KDM4ESMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL6624998 | 0.81 | KDM4E (0.41) | KDM4ESMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL6625176 | 0.78 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL6625856 | 0.76 | KDM4E (0.53) | KDM4ESMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL6623597 | 0.76 | KDM4E (0.46) | KDM4ESMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL6623332 | 0.76 | KDM4E (0.53) | KDM4ESMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL6627873 | 0.76 | KDM4E (0.46) | KDM4ESMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL6626524 | 0.75 | KDM4E (0.45) | KDM4ESMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL6626092 | 0.73 | KDM4E (0.57) | KDM4ESMN1; SMN2ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976754-B1 | REMEDIES/PREVENTIVES FOR RESPIRATORY DISEASES | POLA CHEM IND INC (JP) | 2004-07-14 | — | — | EP | disclosed |
| US-6329382-B1 | TREATMENT OF RESPIRATORY DISEASES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-0976754-A1 | REMEDIES/PREVENTIVES FOR RESPIRATORY DISEASES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-02-02 | — | — | EP | disclosed |