Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625277 | 0.89 | KDM4E (0.45) | KDM4ESMN1; SMN2HTTPOLBRECQL | |
| SCHEMBL6622646 | 0.87 | KDM4E (0.44) | KDM4ESMN1; SMN2HTTPOLBRECQL | |
| SCHEMBL9876869 | 0.81 | KDM4E (0.62) | KDM4ESMN1; SMN2HTTALDH1A1GAA | |
| SCHEMBL6624817 | 0.79 | KDM4E (0.49) | KDM4ESMN1; SMN2HTTPOLBRECQL | |
| SCHEMBL6626868 | 0.79 | KDM4E (0.49) | KDM4ESMN1; SMN2HTTALDH1A1GAA | |
| SCHEMBL8177307 | 0.78 | ALDH1A1 (0.42) | POLBALDH1A1NPC1RAB9A | |
| SCHEMBL6624998 | 0.77 | KDM4E (0.41) | KDM4ESMN1; SMN2HTTPOLBRECQL | |
| SCHEMBL6622385 | 0.77 | KDM4E (0.48) | KDM4ESMN1; SMN2HTTALDH1A1GAA | |
| SCHEMBL6628338 | 0.77 | KDM4E (0.50) | KDM4ESMN1; SMN2HTTALDH1A1GAA | |
| SCHEMBL6626852 | 0.77 | KDM4E (0.50) | KDM4ESMN1; SMN2HTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976754-B1 | REMEDIES/PREVENTIVES FOR RESPIRATORY DISEASES | POLA CHEM IND INC (JP) | 2004-07-14 | — | — | EP | disclosed |
| US-6329382-B1 | TREATMENT OF RESPIRATORY DISEASES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-0976754-A1 | REMEDIES/PREVENTIVES FOR RESPIRATORY DISEASES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-02-02 | — | — | EP | disclosed |