Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | GAA | P10253 | 6/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | GLA | P06280 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4889683 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL23499977 | 0.82 | KDM4E (0.72) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL23276640 | 0.82 | KDM4E (0.72) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL6179565 | 0.82 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL21438254 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL5236476 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL8370420 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL28195038 | 0.79 | HTR2A (0.50) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL8372337 | 0.79 | HSD17B10 (0.46) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL8369219 | 0.79 | POLB (0.47) | KDM4EALDH1A1GAAHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107523603-B | Method for preparing cefaclor by enzyme method | 长沙凯晓生物科技有限公司 | 2020-12-29 | — | — | CN | disclosed |
| EP-1474140-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | Pharmagene Laboratories Ltd (GB) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068226-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |