Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4467878 | 0.86 | MAPT (0.42) | ALDH1A1MEN1KMT2AMAPTPPARG | |
| SCHEMBL5317616 | 0.83 | MAPT (0.45) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1451665 | 0.77 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5474039 | 0.76 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3533766 | 0.74 | MAPT (0.40) | ALDH1A1MEN1KMT2AMAPTPPARG | |
| SCHEMBL6664931 | 0.74 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1198661 | 0.71 | MEN1 (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL16399145 | 0.71 | MEN1 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4463226 | 0.70 | PPARD (0.44) | MAPTPPARGPPARAPPARD | |
| SCHEMBL1198261 | 0.70 | MEN1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480642-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003072102-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |