SCHEMBL662302

SCHEMBL662302

FC(F)c1ccc(C(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.38
PGK2 P07205 1/20 0.38
NOTUM Q6P988 1/20 0.38
TRPV4 Q9HBA0 1/20 0.37
KIF11 P52732 1/20 0.37
DAO P14920 2/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
MRGPRX4 Q96LA9 1/20 0.31
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL9813321 0.96 NOTUM (0.37) PGK1PGK2NOTUMTRPV4KIF11
SCHEMBL4048358 0.86 IDO1 (0.48) IDO1TDO2
SCHEMBL11274191 0.83 MAPT (0.50) KIF11
SCHEMBL14501582 0.83 TRPV4 (0.35) PGK1PGK2NOTUMTRPV4KIF11
SCHEMBL14501581 0.83 TSHR (0.50) PGK1PGK2NOTUMTRPV4KIF11
SCHEMBL1713601 0.83 CA1 (0.32) PGK1PGK2NOTUMTRPV4KIF11
SCHEMBL249690 0.83 CYP2A6 (0.50) KIF11
SCHEMBL979900 0.83 NOTUM (0.32) PGK1PGK2NOTUMTRPV4KIF11
SCHEMBL21670832 0.83 TRPV4 (0.35) PGK1PGK2NOTUMTRPV4KIF11
SCHEMBL4547938 0.83 TYR (0.46) TRPV4IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240417531-A1 METHOD FOR PRODUCING SELF-HEALING ORGANIC-INORGANIC MATERIALS ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN NANOCIENCIAS "CIC nanoGUNE" (ES) 2024-12-19 US claimed
EP-4419603-A1 METHOD FOR PRODUCING SELF-HEALING ORGANIC-INORGANIC MATERIALS ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN NANOCIENCIAS "CIC nanoGUNE" (ES) 2024-08-28 EP claimed
CN-118437610-A Corrosion-resistant low-carbon steel pipe and preparation method thereof 淮安市逸臣精密机械有限公司 2024-08-06 CN claimed
CN-114665677-B Insulation treatment method for motor working under water 贵州航天林泉电机有限公司 2023-09-05 CN claimed
CN-114534925-B Collophanite collecting agent and preparation method thereof 贵州川恒化工股份有限公司 2023-07-14 CN claimed
CN-116332718-A Preparation method of 1, 4-bis (chlorodifluoromethyl) benzene 苏州亚科科技股份有限公司 2023-06-27 CN claimed
WO-2023067111-A1 METHOD FOR PRODUCING SELF-HEALING ORGANIC-INORGANIC MATERIALS ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN NANOCIENCIAS "CIC nanoGUNE" (ES) 2023-04-27 WO claimed
CN-115727064-A Electrically insulating bearing ring, method for producing an electrically insulating bearing ring and bearing 舍弗勒技术股份两合公司 2023-03-03 CN claimed
CN-110769945-B Cosmetic care film comprising a water-soluble layer and a vapor-deposited coating 宝洁公司 2023-01-24 CN claimed
CN-114665677-A Insulation processing method for underwater working motor 贵州航天林泉电机有限公司 2022-06-24 CN claimed
EP-1177581-A2 STR S Trixell S.A.S. (FR) 2002-02-06 EP claimed
EP-1137617-A1 METHOD OF MAKING ALPHA-CHLORO-ALPHA-ALPHA-DIFLUORO AROMATIC COMPOUNDS OCCIDENTAL CHEMICAL CORPORATION (US) 2001-10-04 EP claimed
US-6288290-B1 BROMINATION AND PHOTOBROMINATION OF AROMATIC COMPOUNDS NIPPON SHOKUBAI, CO., LTD. (JP) 2001-09-11 US claimed
WO-2000034215-A1 METHOD OF MAKING α-CHLORO-α,α-DIFLUORO AROMATIC COMPOUNDS OCCIDENTAL CHEMICAL CORPORATION (US) 2000-06-15 WO claimed
WO-2000034214-A1 METHOD OF MAKING α-CHLOROXYLENES OCCIDENTAL CHEMICAL CORPORATION (US) 2000-06-15 WO claimed
WO-2000010194-A2 SOLID STATE RADIATION DETECTOR WITH ENHANCED LIFE DURATION TRIXELL S.A.S. (FR) 2000-02-24 WO claimed
EP-0970938-A1 Preparation of 1,4-bis-(difluoromethyl)benzene AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-01-12 EP claimed
EP-0113185-B2 SELECTIVE BROMINATION PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-07-24 EP claimed
EP-0113185-B1 SELECTIVE BROMINATION PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-04-09 EP claimed
EP-0113185-A1 Selective bromination process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-07-11 EP claimed