Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835799 | 0.85 | MEN1 (0.55) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL6615763 | 0.83 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL27879537 | 0.82 | KMT2A (0.50) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL28249129 | 0.80 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL28335652 | 0.79 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL6215102 | 0.77 | KDM4E (0.68) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL4817380 | 0.77 | MEN1 (0.48) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL10891234 | 0.77 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL2395969 | 0.76 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL11407980 | 0.76 | MEN1 (0.65) | MEN1KMT2AALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399433-A2 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003002553-A2 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-01-09 | — | — | WO | disclosed |