Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GGH | Q92820 | 1/20 | 0.35 |
| ▸ | PGD | P52209 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5545419 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL10896887 | 0.97 | TP53 (0.40) | TP53CA2PGK1PGK2TSHR | |
| Hypophosphorous Acid SCHEMBL8459051 | 0.89 | TP53 (0.35) | TP53CA2PGK1PGK2TSHR | |
| Propylamine SCHEMBL10896765 | 0.83 | GABBR2 (0.39) | TSHRGABRR1GABBR2GABBR1 | |
| SCHEMBL20798068 | 0.78 | TSHR (0.39) | TP53PGK1PGK2TSHRPGD | |
| SCHEMBL254667 | 0.78 | — | — | |
| SCHEMBL29192739 | 0.78 | — | — | |
| Water SCHEMBL23780680 | 0.75 | FOLH1 (0.37) | TP53PGK1PGK2TSHRPGD | |
| SCHEMBL15261448 | 0.75 | FOLH1 (0.37) | TP53PGK1PGK2TSHRPGD | |
| SCHEMBL28384071 | 0.75 | FOLH1 (0.37) | TP53PGK1PGK2TSHRPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417331-A2 | IMPROVED METHOD AND COMPOSITION FOR DETERMINING RESISTANCE TO AN ACETOHYDROXYACID SYNTHASE INHIBITOR | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003014379-A2 | IMPROVED METHOD AND COMPOSITION FOR DETERMINING RESISTANCE TO AN ACETOHYDROXYACID SYNTHASE INHIBITOR | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-20 | — | — | WO | disclosed |