Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | CASP1 | P29466 | 2/20 | 0.64 |
| ▸ | CASP7 | P55210 | 2/20 | 0.64 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.52 |
| ▸ | TUBB | P07437 | 2/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623811 | 0.91 | MEN1 (0.64) | MEN1KMT2AMAPTGAATSHR | |
| SCHEMBL4331880 | 0.88 | MEN1 (0.67) | MEN1KMT2AMAPTGAATSHR | |
| SCHEMBL4323647 | 0.86 | MEN1 (0.69) | MEN1KMT2AMAPTGAATSHR | |
| SCHEMBL6620356 | 0.84 | TUBB4A (0.61) | MEN1KMT2AMAPTGAATSHR | |
| SCHEMBL30628030 | 0.83 | NPC1 (0.72) | MEN1KMT2AMAPTGAATSHR | |
| SCHEMBL28649235 | 0.83 | NPC1 (0.72) | MEN1KMT2AMAPTGAATSHR | |
| SCHEMBL4323810 | 0.82 | MEN1 (0.62) | MEN1KMT2AMAPTGAATSHR | |
| SCHEMBL6623890 | 0.81 | TUBB4A (0.62) | MEN1KMT2AMAPTGAATSHR | |
| SCHEMBL28658257 | 0.80 | MEN1 (0.65) | MEN1KMT2AMAPTGAATSHR | |
| SCHEMBL4325759 | 0.80 | MEN1 (0.83) | MEN1KMT2AMAPTGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230232-B1 | SUBSTITUTED 4H-CHROMENE AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA INC (US) | 2004-02-25 | — | — | EP | claimed |