Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 20/20 | 0.85 |
| ▸ | MMP2 | P08253 | 3/20 | 0.82 |
| ▸ | MMP3 | P08254 | 3/20 | 0.82 |
| ▸ | MMP9 | P14780 | 1/20 | 0.82 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180278 | 1.00 | BMP1 (0.85) | BMP1MMP2MMP3MMP9PDE4A | |
| SCHEMBL6179492 | 0.92 | BMP1 (1.00) | BMP1MMP2MMP3MMP9PDE4A | |
| SCHEMBL6904844 | 0.92 | BMP1 (1.00) | BMP1MMP2MMP3MMP9PDE4A | |
| SCHEMBL6179443 | 0.92 | BMP1 (0.72) | BMP1MMP2MMP3MMP9PDE4A | |
| SCHEMBL6180088 | 0.90 | BMP1 (1.00) | BMP1MMP2MMP3MMP9PDE4A | |
| SCHEMBL6178395 | 0.90 | BMP1 (1.00) | BMP1MMP2MMP3MMP9PDE4A | |
| SCHEMBL6180167 | 0.90 | BMP1 (1.00) | BMP1MMP2MMP3MMP9PDE4A | |
| SCHEMBL6179973 | 0.86 | BMP1 (1.00) | BMP1MMP2MMP3MMP9PDE4A | |
| SCHEMBL6179858 | 0.86 | BMP1 (0.85) | BMP1MMP2MMP3MMP9PDE4A | |
| SCHEMBL6179181 | 0.85 | BMP1 (0.78) | BMP1MMP2MMP3MMP9PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373231-A1 | 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID PCP INHIBITORS | Pfizer Limited (GB) | 2004-01-02 | — | — | EP | claimed |
| WO-2002079175-A1 | 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID PCP INHIBITORS | PFIZER LIMITED (GB) | 2002-10-10 | — | — | WO | claimed |