Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627867 | 0.98 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL6623531 | 0.97 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL6628127 | 0.96 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL6624748 | 0.85 | BCL6 (0.43) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL8188307 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL6622522 | 0.83 | BCL6 (0.43) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL6627418 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL6629334 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL6623982 | 0.82 | BCL6 (0.43) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL6624483 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976754-B1 | REMEDIES/PREVENTIVES FOR RESPIRATORY DISEASES | POLA CHEM IND INC (JP) | 2004-07-14 | — | — | EP | disclosed |
| US-6329382-B1 | TREATMENT OF RESPIRATORY DISEASES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-0976754-A1 | REMEDIES/PREVENTIVES FOR RESPIRATORY DISEASES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-02-02 | — | — | EP | disclosed |