SCHEMBL6623693

SCHEMBL6623693

Cc1cc(NC(=O)CC(=O)O)c2c(c1Oc1ccc(O)c(CCC(C)C)c1)CCC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 20/20 1.00
THRA P10827 16/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5402447 0.91 THRB (1.00) THRBTHRA
SCHEMBL5394393 0.89 THRB (1.00) THRBTHRA
SCHEMBL5391947 0.88 THRB (1.00) THRBTHRA
SCHEMBL31567830 0.88 THRB (1.00) THRBTHRA
SCHEMBL5396284 0.87 THRB (1.00) THRBTHRA
SCHEMBL5401936 0.86 THRB (1.00) THRBTHRA
SCHEMBL5391277 0.86 THRB (1.00) THRBTHRA
SCHEMBL5397475 0.85 THRB (0.82) THRBTHRA
SCHEMBL31567828 0.85 THRB (1.00) THRBTHRA
SCHEMBL5397740 0.85 THRB (1.00) THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1471049-A1 NOVEL THYROID HORMONE RECEPTOR LIGAND, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND USE THEREOF Kissei Pharmaceutical Co., Ltd. (JP) 2004-10-27 EP disclosed