Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | DTYMK | P23919 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1717207 | 0.89 | MEN1 (0.78) | MEN1KMT2AHPGDDTYMKCYP1A2 | |
| SCHEMBL8022167 | 0.75 | MEN1 (0.66) | MEN1KMT2AHPGDDTYMK | |
| SCHEMBL12501006 | 0.75 | KMT2A (0.66) | MEN1KMT2AHPGDDTYMKCYP1A2 | |
| SCHEMBL5799473 | 0.72 | HPGD (0.47) | MEN1KMT2AHPGDDAO | |
| SCHEMBL7840035 | 0.72 | MEN1 (0.71) | MEN1KMT2AHPGDDTYMKCYP1A2 | |
| SCHEMBL24495513 | 0.71 | DAO (0.72) | MEN1KMT2AHPGDDAO | |
| SCHEMBL4172709 | 0.71 | HPGD (0.67) | MEN1KMT2AHPGDCYP1A2GRIA1 | |
| SCHEMBL3996660 | 0.71 | HPGD (1.00) | HPGD | |
| SCHEMBL5115615 | 0.71 | HPGD (0.67) | MEN1KMT2AHPGDCYP1A2GRIA1 | |
| 5-Bromouracil SCHEMBL29805 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385831-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083651-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2002-10-24 | — | — | WO | disclosed |