⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Bromouracil SCHEMBL8224638 | 0.87 | DPYD (0.76) | — | |
| 5-Bromouracil SCHEMBL2153057 | 0.87 | GAA (0.47) | — | |
| 5-Bromouracil SCHEMBL1079108 | 0.87 | MAPT (0.76) | — | |
| 5-Bromouracil SCHEMBL5449794 | 0.87 | DPYD (0.42) | — | |
| 5-Bromouracil SCHEMBL28326183 | 0.84 | ALDH1A1 (0.42) | — | |
| Hypoxanthine SCHEMBL28275165 | 0.80 | ALDH1A1 (0.60) | — | |
| 5-Bromouracil SCHEMBL27606202 | 0.78 | CRBN (0.38) | — | |
| 5-Bromouracil SCHEMBL28273195 | 0.78 | DPYD (0.35) | — | |
| Xanthine SCHEMBL8159665 | 0.77 | ACHE (0.72) | — | |
| SCHEMBL11739894 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 54236 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139254-A1 | INTERFERING RNA FOR INHIBITING TOP1 GENE EXPRESSION AND USE THEREOF | JENKEM TECH CO LTD BEIJING (CN) | 2026-05-21 | — | — | US | claimed |
| WO-2026106497-A2 | FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION | SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) | 2026-05-21 | — | — | WO | claimed |
| US-12630827-B2 | Antisense oligonucleotides targeting SCN2A for the treatment of SCN1A encephalopathies | ROGCON, INC. (US) | 2026-05-19 | — | — | US | claimed |
| CN-122029177-A | Oligonucleotides containing multiple ligands and/or lipids | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122028913-A | Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122029176-A | Containing a plurality of oligonucleotides modified oligonucleotides | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-3458464-B1 | STEREOSELECTIVE SYNTHESIS OF PHOSPHOROTHIOATE OLIGORIBONUCLEOTIDES | ETH ZUERICH (CH) | 2026-04-15 | — | — | EP | claimed |
| US-12596118-B2 | Oligonucleotides for inducing paternal UBE3A expression | HOFFMANN-LA ROCHE INC. (US) | 2026-04-07 | — | — | US | claimed |
| US-12595282-B1 | Method for synthesizing nucleotide strands | HONGENE BIOTECH PTE. LTD. (SG) | 2026-04-07 | — | — | US | claimed |
| US-12577554-B2 | Methods for purification of messenger RNA | TRANSLATE BIO, INC. (US) | 2026-03-17 | — | — | US | claimed |
| EP-0105360-A4 | ANTIBODIES HAVING DUAL SPECIFICITIES, THEIR PREPARATION AND USES THEREFOR. | HYBRITECH INC (US) | 1986-07-08 | — | — | EP | claimed |
| EP-0169787-A1 | Use of oligonucleotides bonded to an intercalating agent as drugs | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1986-01-29 | — | — | EP | claimed |
| WO-1985002415-A1 | NON RADIOACTIVE PROBE AND PROCESS FOR THE CHARACTERIZATION OF A DTERMINED NUCLEOTIDE SEQUENCE AND MEANS FOR THE PRODUCTION OF SAID NON RADIOACTIVE PROBE | INSTITUT PASTEUR (FR) | 1985-06-06 | — | — | WO | claimed |
| EP-0143059-A1 | Non-radioactive probe and process for the characterization of a particular nucleotide sequence, and means for the production of this non-radioactive probe | INSTITUT PASTEUR (FR) | 1985-05-29 | — | — | EP | claimed |
| US-4474748-A | ANTIBIOTICS, FUNGICIDES, ANTISEPTICS | JOHNSON & JOHNSON (US) | 1984-10-02 | — | — | US | claimed |
| EP-0117777-A1 | Compounds containing an oligonucleotide bonded to an intercallating agent, a process for their preparation and their application | Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1984-09-05 | — | — | EP | claimed |
| EP-0105360-A1 | ANTIBODIES HAVING DUAL SPECIFICITIES, THEIR PREPARATION AND USES THEREFOR | HYBRITECH INCORPORATED (US) | 1984-04-18 | — | — | EP | claimed |
| EP-0103464-A2 | Diaminopyrimidines and their production | WARNER-LAMBERT COMPANY (US) | 1984-03-21 | — | — | EP | claimed |
| EP-0098122-A2 | Processes for producing L-proline by fermentation | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1984-01-11 | — | — | EP | claimed |
| WO-1983003679-A1 | ANTIBODIES HAVING DUAL SPECIFICITIES, THEIR PREPARATION AND USES THEREFOR | HYBRITECH INC (US) | 1983-10-27 | — | — | WO | claimed |