Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.44 |
| ▸ | THRA | P10827 | 11/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5393741 | 0.91 | MAOB (0.43) | THRBTHRA | |
| SCHEMBL5401387 | 0.85 | THRB (0.50) | THRBTHRA | |
| SCHEMBL5397627 | 0.85 | THRB (0.43) | THRBTHRARORCGLRA1 | |
| SCHEMBL5404292 | 0.85 | THRB (0.43) | THRBTHRARORCGLRA1 | |
| SCHEMBL5399732 | 0.85 | THRB (0.54) | THRBTHRARORCGLRA1 | |
| SCHEMBL5396862 | 0.85 | THRB (0.44) | THRBTHRARORCGLRA1 | |
| SCHEMBL5401799 | 0.84 | THRB (0.43) | THRBTHRARORC | |
| SCHEMBL5398175 | 0.84 | THRB (0.43) | THRBTHRARORC | |
| SCHEMBL5401632 | 0.83 | THRB (0.50) | THRBTHRA | |
| SCHEMBL6623182 | 0.83 | THRB (0.47) | THRBTHRARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471049-A1 | NOVEL THYROID HORMONE RECEPTOR LIGAND, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-10-27 | — | — | EP | disclosed |