Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | APOL1 | O14791 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627765 | 0.86 | PARP1 (0.44) | PARP1MTNR1AMTNR1B | |
| SCHEMBL6625366 | 0.85 | HTT (0.48) | PARP1ALDH1A1 | |
| SCHEMBL6623518 | 0.83 | CRBN (0.48) | PARP1ALDH1A1 | |
| SCHEMBL6623902 | 0.82 | PARP1 (0.44) | PARP1ALDH1A1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL6624623 | 0.81 | PARP1 (0.41) | PARP1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL6622849 | 0.80 | TAOK3 (0.38) | PARP1ALDH1A1TAOK3 | |
| SCHEMBL6624826 | 0.80 | PARP1 (0.45) | PARP1 | |
| Hydrochloric Acid SCHEMBL6628628 | 0.80 | PARP1 (0.41) | PARP1S1PR1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL6625432 | 0.79 | PARP1 (0.44) | PARP1 | |
| SCHEMBL6625520 | 0.79 | MEN1 (0.48) | PARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |