Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624826 | 0.86 | PARP1 (0.45) | PARP1HTR2AKCNH2HTR2CDRD2 | |
| SCHEMBL6624461 | 0.82 | RB1 (0.46) | PARP1HTR2AKCNH2HTR2CDRD2 | |
| SCHEMBL6622618 | 0.81 | CDC42 (0.46) | PARP1HTR2AKCNH2HTR2CDRD2 | |
| SCHEMBL6627765 | 0.81 | PARP1 (0.44) | PARP1 | |
| SCHEMBL6623902 | 0.81 | PARP1 (0.44) | PARP1HTR2AKCNH2HTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL6628628 | 0.81 | PARP1 (0.41) | PARP1HTR2AKCNH2HTR2CDRD2 | |
| SCHEMBL6625366 | 0.80 | HTT (0.48) | PARP1DDB1CRBN | |
| SCHEMBL6624248 | 0.79 | PARP1 (0.42) | PARP1 | |
| SCHEMBL6624045 | 0.79 | PARP1 (0.48) | PARP1HTR2AKCNH2HTR2CDRD2 | |
| SCHEMBL6622880 | 0.79 | PARP1 (0.48) | PARP1HTR2AKCNH2HTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |