Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 14/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622016 | 0.99 | HTR2C (0.48) | HTR2CCYP19A1NOS2 | |
| SCHEMBL3842816 | 0.80 | HTR2C (0.51) | HTR2CCYP19A1NOS2 | |
| SCHEMBL6100478 | 0.76 | HTR2C (0.47) | HTR2CNOS2 | |
| SCHEMBL6196420 | 0.74 | HTR2C (0.45) | HTR2CNOS2 | |
| SCHEMBL15606087 | 0.73 | CYP19A1 (0.50) | HTR2CCYP19A1 | |
| SCHEMBL6198185 | 0.73 | HTR2C (0.43) | HTR2CNOS2 | |
| SCHEMBL9385024 | 0.73 | HTR2C (0.47) | HTR2C | |
| SCHEMBL914478 | 0.71 | NOS2 (0.43) | HTR2CNOS2 | |
| SCHEMBL13211525 | 0.70 | CYP19A1 (0.42) | HTR2CCYP19A1 | |
| SCHEMBL1339830 | 0.68 | HTR2C (0.38) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181294-B1 | NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN | SANOCHEMIA PHARMAZEUTIKA AG (AT) | 2004-03-31 | — | — | EP | disclosed |
| EP-1181294-A1 | NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN | Sanochemia Pharmazeutika Aktiengesellschaft (AT) | 2002-02-27 | — | — | EP | disclosed |
| WO-2001074820-A1 | NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN | SANOCHEMIA PHARMAZEUTIKA AKTIENGESELLSCHAFT (AT) | 2001-10-11 | — | — | WO | disclosed |