Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 10/20 | 0.64 |
| ▸ | AVPR2 | P30518 | 8/20 | 0.64 |
| ▸ | OXTR | P30559 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622674 | 0.85 | AVPR2 (0.72) | AVPR1AAVPR2OXTR | |
| SCHEMBL6623276 | 0.83 | AVPR2 (0.55) | AVPR1AAVPR2OXTR | |
| SCHEMBL6623505 | 0.82 | AVPR1A (0.65) | AVPR1AAVPR2 | |
| SCHEMBL6623931 | 0.82 | AVPR1A (0.73) | AVPR1AAVPR2OXTR | |
| SCHEMBL6623379 | 0.81 | AVPR1A (0.69) | AVPR1AAVPR2OXTR | |
| SCHEMBL6623522 | 0.80 | LMNA (0.69) | AVPR1AAVPR2OXTR | |
| SCHEMBL6624843 | 0.79 | AVPR1A (0.77) | AVPR1AAVPR2 | |
| SCHEMBL13403212 | 0.79 | AVPR1A (0.85) | AVPR1AAVPR2 | |
| SCHEMBL6623458 | 0.78 | AVPR1A (0.68) | AVPR1AAVPR2 | |
| SCHEMBL7332293 | 0.78 | AVPR1A (0.83) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000062-B1 | TRICYCLIC VASOPRESSIN AGONISTS | WYETH CORP (US) | 2004-09-22 | — | — | EP | claimed |
| US-6831079-B1 | Oral delivery; nitrogen triheterocyclic active material, surfactant, polyethylene glycol with sucrose fatty acid esters and/or polyvinylpyrrolidone | AMERICAN CYANAMID COMPANY | 2004-12-14 | — | — | US | disclosed |
| EP-1000062-B1 | TRICYCLIC VASOPRESSIN AGONISTS | WYETH CORP (US) | 2004-09-22 | — | — | EP | disclosed |
| US-6511974-B1 | Non-peptidic and have good oral bioavailability, specific vasopressin V2 agonists, therefore do not raise blood pressure | WYETH | 2003-01-28 | — | — | US | disclosed |