Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29260156 | 0.87 | ALDH1A1 (0.52) | ALDH1A1CNR1MMP2MMP1MMP3 | |
| SCHEMBL28420260 | 0.87 | ALDH1A1 (0.52) | ALDH1A1CNR1MMP2MMP1MMP3 | |
| SCHEMBL29259791 | 0.83 | TP53 (0.52) | ALDH1A1CNR1MMP2MMP1MMP3 | |
| SCHEMBL29019311 | 0.82 | CNR1 (0.54) | EGFRERBB2ALDH1A1CNR1MMP2 | |
| SCHEMBL14619788 | 0.82 | ALDH1A1 (0.69) | ALDH1A1CNR1MMP2MMP1MMP3 | |
| SCHEMBL28423968 | 0.82 | ALDH1A1 (0.69) | ALDH1A1CNR1MMP2MMP1MMP3 | |
| SCHEMBL29260149 | 0.81 | CNR1 (0.63) | ALDH1A1CNR1CA2POLBCA1 | |
| SCHEMBL29259803 | 0.80 | CNR1 (0.60) | ALDH1A1CNR1MMP2MMP1MMP3 | |
| SCHEMBL22489818 | 0.79 | SLC1A3 (0.43) | ALDH1A1CA2POLBCA1NPSR1 | |
| SCHEMBL26603588 | 0.78 | PFKFB3 (0.43) | ALDH1A1MMP2MMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567453-A | Benzazepine analogs as inhibitors of bruton's tyrosine kinase | 渤健马萨诸塞州股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-110621670-B | Benzazepine analogs as inhibitors of bruton's tyrosine kinase | 比奥根MA公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-109096274-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-110621670-A | Benzazepine analogs as inhibitors of bruton's tyrosine kinase | 比奥根MA公司 | 2019-12-27 | — | — | CN | disclosed |
| EP-1421079-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003010163-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-02-06 | — | — | WO | disclosed |