Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8222171 | 0.99 | POLB (0.40) | POLBPARP1ALDH1A1KDM4EGAA | |
| SCHEMBL6623672 | 0.91 | PARP1 (0.41) | PARP1CD274BCHEMAOAMAOB | |
| SCHEMBL6623902 | 0.86 | PARP1 (0.44) | PARP1ALDH1A1CD274MAOAMAOB | |
| Hydrochloric Acid SCHEMBL6624623 | 0.83 | PARP1 (0.41) | PARP1ALDH1A1CD274MAOAMAOB | |
| SCHEMBL6626911 | 0.80 | PARP1 (0.40) | POLBPARP1ALDH1A1KDM4EGAA | |
| SCHEMBL6627765 | 0.80 | PARP1 (0.44) | POLBPARP1KDM4ECD274LMNA | |
| Hydrochloric Acid SCHEMBL6627074 | 0.80 | PARP1 (0.39) | POLBPARP1ALDH1A1KDM4EGAA | |
| SCHEMBL6625091 | 0.79 | MAPT (0.39) | PARP1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL6622618 | 0.79 | CDC42 (0.46) | PARP1GAACD274 | |
| SCHEMBL6624331 | 0.78 | SCN3A (0.36) | PARP1SMN1; SMN2CD274LMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |