Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6624304 | 0.99 | MAPT (0.38) | MAPTALDH1A1KDM4ESMN1; SMN2PARP1 | |
| SCHEMBL6624000 | 0.80 | PARP1 (0.45) | PARP1ACHE | |
| SCHEMBL6624637 | 0.79 | POLB (0.40) | MAPTALDH1A1KDM4ESMN1; SMN2PARP1 | |
| Hydrochloric Acid SCHEMBL6622794 | 0.79 | PARP1 (0.44) | PARP1ACHE | |
| Hydrochloric Acid SCHEMBL8222171 | 0.78 | POLB (0.40) | MAPTALDH1A1KDM4ESMN1; SMN2PARP1 | |
| SCHEMBL6625270 | 0.76 | HTR1A (0.43) | PARP1MEN1KMT2A | |
| SCHEMBL6625065 | 0.73 | ALOX15 (0.48) | MAPTALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL6623672 | 0.71 | PARP1 (0.41) | PARP1ACHEBCHEMAOAMAOB | |
| SCHEMBL6624045 | 0.71 | PARP1 (0.48) | PARP1 | |
| SCHEMBL6627765 | 0.70 | PARP1 (0.44) | MAPTKDM4EPARP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |