Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR5A | P47898 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.49 |
| ▸ | HTR3B | O95264 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624704 | 0.89 | HTR6 (0.56) | HTR6HTR1AHTR2AHTR7HTR5A | |
| SCHEMBL6625130 | 0.86 | HTR6 (0.52) | HTR6HTR1AHTR2AHTR7HTR5A | |
| SCHEMBL6627594 | 0.82 | HTR6 (0.48) | HTR6HTR1AHTR2AHTR7HTR5A | |
| SCHEMBL30610357 | 0.76 | HTR6 (0.56) | HTR6HTR1AHTR2AHTR7HTR5A | |
| SCHEMBL5374711 | 0.76 | HTR6 (0.56) | HTR6HTR1AHTR2AHTR7HTR5A | |
| SCHEMBL13798789 | 0.73 | HTR6 (0.56) | HTR6HTR1AHTR2AHTR7HTR5A | |
| SCHEMBL6193597 | 0.72 | HTR6 (0.62) | HTR6HTR1AHTR2AHTR7HTR5A | |
| SCHEMBL6191880 | 0.72 | HTR6 (0.52) | HTR6HTR1AHTR2AHTR7HTR5A | |
| SCHEMBL12842522 | 0.72 | HTR6 (0.55) | HTR6HTR1AHTR2AHTR7HTR5A | |
| SCHEMBL7533961 | 0.72 | HTR6 (0.80) | HTR6HTR1AHTR2AHTR7HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |