Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628602 | 0.82 | POLB (0.61) | PDE4BALDH1A1KDM4EGAATPMT | |
| SCHEMBL6626908 | 0.81 | PDE4B (0.45) | PDE4BALDH1A1KDM4EGAATPMT | |
| SCHEMBL5080187 | 0.80 | PDE4B (0.54) | PDE4BALDH1A1KDM4EPOLBMAPK1 | |
| SCHEMBL28656864 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL25187287 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL14495122 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAATPMTPOLB | |
| SCHEMBL6622371 | 0.75 | PDE4B (0.57) | PDE4BALDH1A1KDM4EPOLBMAPK1 | |
| SCHEMBL11741914 | 0.75 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAATPMTSMN1; SMN2 | |
| SCHEMBL1191343 | 0.75 | TPMT (0.79) | ALDH1A1KDM4EGAATPMTPOLB | |
| SCHEMBL2425789 | 0.75 | GALK1 (0.45) | ALDH1A1KDM4EGAATPMTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |