Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30371825 | 1.00 | TAAR1 (0.47) | TAAR1AOC3PYCR1IDO1PNMT | |
| SCHEMBL6624949 | 1.00 | TAAR1 (0.47) | TAAR1AOC3PYCR1IDO1PNMT | |
| SCHEMBL6624263 | 0.79 | HTT (0.41) | TAAR1KMT2AALDH1A1BACE1LMNA | |
| SCHEMBL6624262 | 0.79 | HTT (0.41) | TAAR1KMT2AALDH1A1BACE1LMNA | |
| SCHEMBL6623797 | 0.79 | IDO1 (0.44) | PYCR1IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6623793 | 0.79 | IDO1 (0.44) | PYCR1IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6624427 | 0.76 | SLC6A2 (0.38) | KMT2ASLC6A2SLC6A4SLC6A3SMN1; SMN2 | |
| SCHEMBL6624425 | 0.76 | SLC6A2 (0.38) | KMT2ASLC6A2SLC6A4SLC6A3SMN1; SMN2 | |
| SCHEMBL16344986 | 0.74 | TAAR1 (0.47) | TAAR1AOC3IDO1PNMTKMT2A | |
| SCHEMBL15094131 | 0.74 | TAAR1 (0.47) | TAAR1AOC3IDO1PNMTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |