Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12021475 | 0.83 | KDM4E (0.47) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL31347497 | 0.83 | TAAR1 (0.54) | KDM4EMAPTALDH1A1GAABACE1 | |
| SCHEMBL1099257 | 0.83 | CYP4F2 (0.46) | KDM4EMAPTALDH1A1GAACA2 | |
| SCHEMBL4720461 | 0.80 | ALDH1A1 (0.52) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL1238835 | 0.80 | ALDH1A1 (0.52) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL30986331 | 0.80 | ALDH1A1 (0.52) | KDM4EMAPTALDH1A1GAAALOX5 | |
| SCHEMBL1068301 | 0.79 | NPC1 (0.59) | MAPTCA2TP53HSD17B10NPC1 | |
| SCHEMBL13577064 | 0.79 | TAAR1 (0.56) | ALDH1A1TP53HSD17B10NPC1PKM | |
| SCHEMBL4301346 | 0.78 | MAOB (0.54) | SMN1; SMN2TAAR1 | |
| SCHEMBL1931989 | 0.77 | FFAR1 (0.50) | CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392644-A1 | CINNAMIDE DERIVATIVES AS KCNQ POTASSIUM CHANNEL MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002096858-A1 | CINNAMIDE DERIVATIVES AS KCNQ POTASSIUM CHANNEL MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-12-05 | — | — | WO | disclosed |