Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.80 |
| ▸ | CDK1 | P06493 | 1/20 | 0.79 |
| ▸ | CDK2 | P24941 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6477004 | 0.90 | GSK3B (1.00) | GSK3BCDK1CDK2CYP1A2 | |
| SCHEMBL6477490 | 0.90 | GSK3B (1.00) | GSK3BCDK1CDK2CYP1A2 | |
| SCHEMBL1461781 | 0.90 | GSK3B (1.00) | GSK3BCDK1CDK2CYP1A2 | |
| SCHEMBL1461347 | 0.89 | GSK3B (1.00) | GSK3BCDK1CDK2CYP1A2 | |
| SCHEMBL6479434 | 0.86 | GSK3B (1.00) | GSK3BCDK1CDK2CYP1A2 | |
| SCHEMBL6486735 | 0.85 | GSK3B (1.00) | GSK3BCDK1CDK2CYP1A2 | |
| SCHEMBL1461843 | 0.84 | GSK3B (1.00) | GSK3BCDK1CDK2CYP1A2 | |
| SCHEMBL31061079 | 0.82 | GSK3B (1.00) | GSK3BCDK1CDK2CYP1A2 | |
| SCHEMBL1461361 | 0.82 | GSK3B (1.00) | GSK3BCDK1CDK2CYP1A2 | |
| SCHEMBL6628699 | 0.81 | GSK3B (0.89) | GSK3BCDK1CDK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487804-A2 | AMINOINDAZOLE DERIVATIVES AS PROTEIN-KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003078403-A2 | DERIVES D’AMINOINDAZOLES COMME INHIBITEURS DE PROTEINE-KINASE | AVENTIS PHARMA S.A. (FR) | 2003-09-25 | — | — | WO | disclosed |