Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.47 |
| ▸ | ATR | Q13535 | 4/20 | 0.47 |
| ▸ | ATRIP | Q8WXE1 | 4/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626337 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1GAAHPGDPIK3CB | |
| SCHEMBL6626670 | 0.93 | HRH4 (0.52) | KDM4EALDH1A1GAAHPGDPIK3CB | |
| SCHEMBL6626680 | 0.93 | HRH4 (0.52) | KDM4EALDH1A1GAAHPGDPIK3CB | |
| SCHEMBL6623933 | 0.92 | PIK3CB (0.62) | KDM4EALDH1A1GAAHPGDPIK3CB | |
| SCHEMBL6626223 | 0.92 | PIK3CB (0.62) | KDM4EALDH1A1GAAHPGDPIK3CB | |
| SCHEMBL6626217 | 0.92 | PIK3CB (0.62) | KDM4EALDH1A1GAAHPGDPIK3CB | |
| SCHEMBL6623928 | 0.92 | PIK3CB (0.62) | KDM4EALDH1A1GAAHPGDPIK3CB | |
| SCHEMBL7784942 | 0.88 | PIK3CB (0.61) | KDM4EALDH1A1GAAHPGDPIK3CB | |
| SCHEMBL6624104 | 0.88 | PIK3CB (0.61) | KDM4EALDH1A1GAAHPGDPIK3CB | |
| SCHEMBL6625743 | 0.88 | PDCD1 (0.47) | KDM4EALDH1A1GAAHPGDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020462-B1 | HETEROCYCLIC COMPOUNDS AND ANTITUMOR AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | ZENYAKU KOGYO KK (JP) | 2004-02-11 | — | — | EP | disclosed |
| US-6251900-B1 | Heterocyclic compounds and antitumor agent containing the same as active ingredient | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-1020462-A1 | HETEROCYCLIC COMPOUNDS AND ANTITUMOR AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-07-19 | — | — | EP | disclosed |