Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 6/20 | 0.41 |
| ▸ | CCR1 | P32246 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626976 | 1.00 | CCR3 (0.41) | CCR3CCR1LMNATSHRMAPK1 | |
| SCHEMBL6629019 | 0.88 | CASP1 (0.43) | CCR3CCR1LMNATSHRMAPK1 | |
| SCHEMBL7086596 | 0.88 | CASP1 (0.43) | CCR3CCR1LMNATSHRMAPK1 | |
| SCHEMBL6627597 | 0.76 | CASP1 (0.44) | CCR3CCR1LMNAALDH1A1HPGD | |
| SCHEMBL6626382 | 0.76 | CASP1 (0.44) | CCR3CCR1LMNAALDH1A1HPGD | |
| SCHEMBL6627592 | 0.75 | CASP1 (0.41) | NPY1R | |
| SCHEMBL6627596 | 0.75 | CASP1 (0.41) | NPY1R | |
| SCHEMBL6628216 | 0.75 | CASP1 (0.40) | LMNAALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL6628214 | 0.75 | CASP1 (0.40) | LMNAALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL6631474 | 0.73 | CASP1 (0.46) | LMNAALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246824-B1 | CARBOXAMIDE DIAZEPIN DERIVATIVES, PREPARATION METHOD, USE AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | AVENTIS PHARMA SA (FR) | 2004-06-09 | — | — | EP | claimed |