Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 8/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033026 | 0.76 | POLB (0.67) | KDM4ERXFP1L3MBTL1CASP3POLB | |
| SCHEMBL22033363 | 0.75 | POLB (0.66) | KDM4ERXFP1L3MBTL1CASP3POLB | |
| SCHEMBL14344748 | 0.75 | POLB (0.59) | KDM4ERXFP1L3MBTL1CASP3POLB | |
| SCHEMBL11839073 | 0.75 | KDM4E (0.56) | KDM4ERXFP1L3MBTL1CASP3POLB | |
| SCHEMBL12857746 | 0.74 | CASP3 (0.78) | KDM4ERXFP1L3MBTL1CASP3POLB | |
| SCHEMBL12857607 | 0.73 | CASP3 (1.00) | KDM4ERXFP1L3MBTL1CASP3POLB | |
| SCHEMBL11830879 | 0.73 | KDM4E (0.57) | KDM4ERXFP1L3MBTL1CASP3POLB | |
| SCHEMBL3379082 | 0.73 | KDM4E (0.58) | KDM4ERXFP1L3MBTL1CASP3POLB | |
| SCHEMBL4455080 | 0.73 | KDM4E (0.73) | KDM4ERXFP1L3MBTL1CASP3POLB | |
| SCHEMBL7960619 | 0.72 | KDM4E (1.00) | KDM4ERXFP1L3MBTL1CASP3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408962-A1 | SUBSTITUTED ISOINDOLES AND THE USE THEREOF | Bayer HealthCare AG (DE) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003007942-A1 | SUBSTITUTED ISOINDOLES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-01-30 | — | — | WO | disclosed |