Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.46 |
| ▸ | BBOX1 | O75936 | 9/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL5028780 | 0.98 | LMNA (0.48) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Succinic Acid SCHEMBL28245312 | 0.96 | CYP3A4 (0.52) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Succinic Acid SCHEMBL27349026 | 0.89 | LMNA (0.57) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Succinic Acid SCHEMBL3191898 | 0.89 | MEN1 (0.57) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Succinic Acid SCHEMBL28245315 | 0.89 | LMNA (0.57) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Succinic Acid SCHEMBL6627654 | 0.87 | CYP3A4 (0.62) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Succinic Acid SCHEMBL27500998 | 0.87 | LMNA (0.55) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Succinic Acid SCHEMBL27491383 | 0.87 | MEN1 (0.62) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Succinic Acid SCHEMBL27500506 | 0.87 | LMNA (0.60) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Succinic Acid SCHEMBL28127025 | 0.85 | CYP3A4 (0.65) | LMNAMEN1KMT2ACYP3A4SLC5A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107519136-B | Succinylcholine chloride freeze-dried preparation and preparation method thereof | 西安力邦医药科技有限责任公司 | 2020-07-14 | — | — | CN | disclosed |
| EP-0976754-B1 | REMEDIES/PREVENTIVES FOR RESPIRATORY DISEASES | POLA CHEM IND INC (JP) | 2004-07-14 | — | — | EP | disclosed |
| US-6329382-B1 | TREATMENT OF RESPIRATORY DISEASES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-0976754-A1 | REMEDIES/PREVENTIVES FOR RESPIRATORY DISEASES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-02-02 | — | — | EP | disclosed |