Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353106 | 0.83 | KDM4E (0.47) | SMN1; SMN2ALDH1A1KDM4CKDM4EASPH | |
| SCHEMBL17881864 | 0.83 | CYP2A6 (0.33) | P2RX7CYP2A6 | |
| SCHEMBL353138 | 0.81 | SIRT3 (0.46) | SMN1; SMN2P2RX7ALDH1A1KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL5796678 | 0.79 | SIRT3 (0.44) | SMN1; SMN2P2RX7ALDH1A1KDM4ERAB9A | |
| SCHEMBL30590435 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2P2RX7ALDH1A1KDM4CKDM4E | |
| SCHEMBL1119080 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1KDM4CKDM4EPOLB | |
| SCHEMBL27554852 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1KDM4CKDM4EASPH | |
| SCHEMBL13041779 | 0.78 | KDM4E (0.47) | SMN1; SMN2ALDH1A1KDM4CKDM4EPOLB | |
| SCHEMBL25828300 | 0.76 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1KDM4CKDM4EASPH | |
| SCHEMBL11131895 | 0.75 | HPGD (0.56) | SMN1; SMN2ALDH1A1KDM4ERAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935248-B1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2018-02-28 | — | — | EP | disclosed |
| EP-0974602-B1 | Catalyst and process for hydrogenating olefinically unsaturated compound | JSR CORP (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-6291596-B1 | CONTACTING OLEFINICALLY UNSATURATED COMPOUND WITH HYDROGEN IN THE PRESENCE OF A HYDROGENATION CATALYST COMPRISING TITANIUM OR ZIRCONIUM OR HAFNIUM COMPOUND IN AN INERT, ORGANIC SOLVENT | JSR CORPORATION (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-0974602-A1 | Catalyst and process for hydrogenating olefinically unsaturated compound | JSR Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |