Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.98 |
| ▸ | FNTB | P49356 | 5/20 | 0.98 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628596 | 0.98 | FNTA (0.98) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL7871133 | 0.91 | FNTA (0.85) | FNTAFNTBTDP1 | |
| Lithium Ion SCHEMBL6628591 | 0.91 | FNTA (0.85) | FNTAFNTB | |
| SCHEMBL7871129 | 0.91 | FNTA (0.85) | FNTAFNTBTDP1 | |
| SCHEMBL6627300 | 0.88 | FNTA (0.79) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL6627296 | 0.88 | FNTA (0.79) | FNTAFNTBPGGT1BTDP1 | |
| Hydrochloric Acid SCHEMBL7870253 | 0.87 | FNTA (0.78) | FNTAFNTBPGGT1BTDP1 | |
| Hydrochloric Acid SCHEMBL7870250 | 0.87 | FNTA (0.78) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL6778067 | 0.80 | FNTA (0.67) | FNTAFNTB | |
| SCHEMBL6778062 | 0.80 | FNTA (0.67) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2004-09-15 | — | — | EP | claimed |
| EP-0986384-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 2000-03-22 | — | — | EP | claimed |
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |