Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.85 |
| ▸ | FNTB | P49356 | 8/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ICMT | O60725 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871133 | 1.00 | FNTA (0.85) | FNTAFNTBTDP1ICMT | |
| Lithium SCHEMBL6628599 | 0.91 | FNTA (0.98) | FNTAFNTBTDP1 | |
| SCHEMBL6628596 | 0.91 | FNTA (0.98) | FNTAFNTBTDP1 | |
| Lithium Ion SCHEMBL6628591 | 0.90 | FNTA (0.85) | FNTAFNTB | |
| SCHEMBL6774843 | 0.83 | FNTA (0.65) | FNTAFNTBTDP1 | |
| SCHEMBL6774846 | 0.83 | FNTA (0.65) | FNTAFNTBTDP1 | |
| SCHEMBL6624287 | 0.81 | FNTA (0.62) | FNTAFNTBTDP1 | |
| SCHEMBL6774699 | 0.81 | FNTA (0.65) | FNTAFNTBTDP1 | |
| SCHEMBL6775608 | 0.81 | FNTA (0.62) | FNTAFNTBTDP1 | |
| SCHEMBL6624253 | 0.81 | FNTA (0.65) | FNTAFNTBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |