Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.62 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031494 | 0.89 | KDM4E (0.60) | CSNK2A1CHRNB2CHRNA7CHRNA4KDM4E | |
| SCHEMBL29354243 | 0.89 | CSNK2A1 (0.77) | CSNK2A1CHRNB2CHRNA7CHRNA4SLC6A4 | |
| SCHEMBL6029334 | 0.89 | CSNK2A1 (0.77) | CSNK2A1CHRNB2CHRNA7CHRNA4SLC6A4 | |
| Bromogramine SCHEMBL30279666 | 0.77 | SLC6A4 (0.68) | CSNK2A1KDM4EMEN1ALDH1A1CYP3A4 | |
| Bromogramine SCHEMBL1196680 | 0.77 | SLC6A4 (0.68) | CSNK2A1KDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL2005588 | 0.77 | CSNK2A1 (1.00) | CSNK2A1SLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL15678339 | 0.76 | SLC6A4 (0.56) | KDM4EMEN1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL22122400 | 0.75 | CHRNB2 (0.60) | CSNK2A1CHRNB2CHRNA7CHRNA4SLC6A4 | |
| SCHEMBL18824168 | 0.75 | HTR2A (0.68) | CHRNB2CHRNA7CHRNA4CYP2D6SLC6A4 | |
| SCHEMBL15074715 | 0.74 | HTR2A (0.59) | CSNK2A1CHRNB2CHRNA7CHRNA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325011-B1 | METHODS AND COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | LILLY CO ELI (US) | 2004-05-06 | — | — | EP | disclosed |