Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 14/20 | 0.73 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6629004 | 0.90 | ADORA3 (0.73) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6628940 | 0.88 | ADORA3 (0.74) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6628541 | 0.87 | ADORA3 (0.74) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL3059034 | 0.84 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6626445 | 0.83 | ADORA3 (0.76) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6628145 | 0.83 | ADORA3 (0.81) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6626444 | 0.82 | ADORA3 (0.73) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6629322 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6626387 | 0.80 | ADORA3 (0.79) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6630614 | 0.78 | ADORA3 (0.77) | ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227098-B1 | TRIAZOLOPURINE DERIVATIVES, DRUG COMPOSITIONS CONTAINING THE SAME AND ADENOSINE A3 RECEPTOR AFFINITIVE AGENTS | OTSUKA PHARMA CO LTD (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-6686343-B1 | Triazolopurine derivatives, pharmaceutical compositions containing the derivatives, and adenosine A3 receptor affinitive agents | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2004-02-03 | — | — | US | disclosed |
| EP-1227098-A1 | TRIAZOLOPURINE DERIVATIVES, DRUG COMPOSITIONS CONTAINING THE SAME AND ADENOSINE A3 RECEPTOR AFFINITIVE AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2002-07-31 | — | — | EP | disclosed |