Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | NNMT | P40261 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628177 | 0.83 | CTNNB1 (0.59) | CTNNB1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL6630091 | 0.80 | CTNNB1 (0.59) | CTNNB1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL6634137 | 0.77 | CTNNB1 (0.55) | CTNNB1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL5971904 | 0.76 | CTNNB1 (0.54) | CTNNB1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL5175230 | 0.75 | HTT (0.73) | CTNNB1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL6629908 | 0.74 | CTNNB1 (0.51) | CTNNB1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL6368241 | 0.74 | CTNNB1 (0.74) | CTNNB1MEN1KMT2ACYP3A4MAPT | |
| Methyl Alcohol SCHEMBL8782982 | 0.74 | CTNNB1 (0.93) | CTNNB1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL1702138 | 0.74 | CTNNB1 (0.68) | CTNNB1LMNAMKNK1MKNK2HTT | |
| SCHEMBL30060692 | 0.74 | CTNNB1 (0.68) | CTNNB1LMNAMKNK1MKNK2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480977-A2 | SUBSTITUTED ARYL COMPOUNDS FOR TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1387830-A1 | NOVEL 4-ANILINOQUINOLINE-3-CARBOXAMIDES | AstraZeneca AB (SE) | 2004-02-11 | — | — | EP | disclosed |
| WO-2003070728-A2 | AZABICYCLO-SUBSTITUTED BENZOYLAMIDES AND THIOAMIDES FOR TREATMENT OF CNS-RELATED DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 2003-08-28 | — | — | WO | disclosed |
| WO-2002092571-A1 | NOVEL 4-ANILINOQUINOLINE-3-CARBOXAMIDES | ASTRAZENECA AB (SE) | 2002-11-21 | — | — | WO | disclosed |