Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 15/20 | 0.61 |
| ▸ | FAAH | O00519 | 9/20 | 0.61 |
| ▸ | CES1 | P23141 | 6/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6062834 | 0.83 | DAGLA (0.56) | DAGLAFAAHCES1 | |
| SCHEMBL6630749 | 0.83 | DAGLA (0.53) | DAGLAFAAHCES1 | |
| SCHEMBL27805184 | 0.83 | DAGLA (0.67) | DAGLAFAAHCES1 | |
| SCHEMBL6062124 | 0.82 | DAGLA (0.57) | DAGLAFAAHCES1 | |
| SCHEMBL6062128 | 0.80 | DAGLA (0.55) | DAGLAFAAHCES1 | |
| SCHEMBL6468442 | 0.80 | DAGLA (0.55) | DAGLAFAAHCES1 | |
| SCHEMBL6630786 | 0.78 | DAGLA (0.52) | DAGLAFAAHCES1 | |
| SCHEMBL6062952 | 0.77 | DAGLA (0.52) | DAGLAFAAHCES1 | |
| SCHEMBL6462869 | 0.77 | DAGLA (0.52) | DAGLAFAAHCES1 | |
| SCHEMBL6631047 | 0.77 | DAGLA (0.52) | DAGLAFAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397340-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002098850-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | disclosed |