Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 15/20 | 0.57 |
| ▸ | FAAH | O00519 | 9/20 | 0.57 |
| ▸ | CES1 | P23141 | 6/20 | 0.57 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631756 | 0.95 | DAGLA (0.52) | DAGLAFAAHCES1XDH | |
| SCHEMBL6062122 | 0.87 | FAAH (0.50) | DAGLAFAAHCES1 | |
| SCHEMBL6631751 | 0.84 | DAGLA (0.42) | DAGLAFAAHCES1XDH | |
| SCHEMBL6062128 | 0.83 | DAGLA (0.55) | DAGLAFAAHCES1XDH | |
| SCHEMBL6631288 | 0.82 | CYP1A2 (0.38) | DAGLAFAAHCES1 | |
| SCHEMBL6628866 | 0.82 | DAGLA (0.61) | DAGLAFAAHCES1 | |
| SCHEMBL6062834 | 0.82 | DAGLA (0.56) | DAGLAFAAHCES1 | |
| SCHEMBL6630786 | 0.80 | DAGLA (0.52) | DAGLAFAAHCES1 | |
| SCHEMBL27805184 | 0.80 | DAGLA (0.67) | DAGLAFAAHCES1 | |
| SCHEMBL6634123 | 0.78 | DAGLA (0.53) | DAGLAFAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694357-A1 | USE OF CATHEPSIN S INHIBITORS FOR TREATING AN IMMUNE RESPONSE CAUSED BY ADMINISTRATION OF A SMALL MOLECULE THERAPEUTIC OR BIOLOGIC | AXYS PHARMACEUTICALS, INC. (US) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058348-A1 | USE OF CATHEPSIN S INHIBITORS FOR TREATING AN IMMUNE RESPONSE CAUSED BY ADMINISTRATION OF A SMALL MOLECULE THERAPEUTIC OR BIOLOGIC | AXYS PHARMACEUTICALS, INC. (US) | 2005-06-30 | — | — | WO | disclosed |