Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 13/20 | 1.00 |
| ▸ | CHRNA4 | P43681 | 13/20 | 1.00 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.62 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5037226 | 1.00 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5374465 | 1.00 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL7250932 | 0.98 | CHRNB2 (0.97) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5038459 | 0.88 | CHRNB2 (0.79) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5377778 | 0.88 | CHRNB2 (0.79) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5384913 | 0.85 | CHRNB2 (0.74) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5388777 | 0.85 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5372528 | 0.85 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5367882 | 0.85 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL5036709 | 0.84 | CHRNB2 (0.72) | CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144413-B1 | 2,5-DIAZABICYCLO 2.2.1]HEPTANE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | SANOFI SYNTHELABO (FR) | 2004-03-17 | — | — | EP | disclosed |
| US-6635645-B1 | Nicotinic receptors dysfunction | SANOFI-SYNTHELABO (FR) | 2003-10-21 | — | — | US | disclosed |