Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5646906 | 0.80 | HPGD (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL5647643 | 0.79 | LMNA (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL5646943 | 0.78 | HPGD (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL11478684 | 0.71 | MEN1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL5649334 | 0.71 | MEN1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL11479057 | 0.70 | MEN1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL5649176 | 0.69 | MEN1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL6631777 | 0.69 | NPC1 (0.44) | ALDH1A1SMN1; SMN2HPGDNPC1LMNA | |
| SCHEMBL11378393 | 0.68 | MEN1 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL11500179 | 0.68 | LMNA (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458374-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051841-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |