Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.68 |
| ▸ | CTSL | P07711 | 17/20 | 0.68 |
| ▸ | CTSS | P25774 | 13/20 | 0.68 |
| ▸ | CTSB | P07858 | 6/20 | 0.68 |
| ▸ | CTSV | O60911 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6629293 | 1.00 | CTSK (0.68) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6629287 | 1.00 | CTSK (0.68) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4767207 | 0.90 | CTSK (0.84) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5096581 | 0.87 | CTSK (0.65) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5096586 | 0.87 | CTSK (0.65) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5099744 | 0.86 | CTSK (0.65) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5099749 | 0.86 | CTSK (0.65) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6628202 | 0.86 | CTSK (0.61) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6628192 | 0.86 | CTSK (0.61) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6628197 | 0.86 | CTSK (0.61) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |